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| Names | |
|---|---|
| IUPAC name 2′-Deoxycytidylic acid | |
| Systematic IUPAC name [(2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
|
| ECHA InfoCard | 100.012.591 |
| MeSH | Deoxycytidine+monophosphate |
| UNII | |
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| Properties | |
| C9H14N3O7P | |
| Molar mass | 307.199 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Deoxycytidine monophosphate (dCMP), also known asdeoxycytidylic acid ordeoxycytidylate in itsconjugate acid and conjugate base forms, respectively, is adeoxynucleotide and one of the fourmonomers that make upDNA. In aDNA double helix, it will base pair withdeoxyguanosine monophosphate.[1]
Deoxycytidine monophosphate is a molecule of interest in treating genetic disorders such as thymidine kinase 2 (TK2) deficiency. In the case ofTK2 deficiency, dCMP in conjunction withdeoxythymidine monophosphate (dTMP) to bypass the deficiency in theTK2 enzyme.[2] Additionally dCMP is an indicator of several metabolite deficiency pathways such as UMP synthase deficiency ororotic aciduria.[3]
