David Crane may refer to:

• David Crane (historian) (fl. 1999–2013), British historian
• David Crane (lawyer) (born 1950), former Chief Prosecutor for the U.N. War Crimes Tribunal for Sierra Leone
• David Crane (politics) (born 1953), political advisor to Arnold Schwarzenegger and lecturer at Stanford University
• David Crane (producer) (born 1957), co-creator of the popular sitcomFriends
• David Crane (programmer) (born 1953), video game designer, programmer and co-founder of Activision
• David W. Crane (born 1959), American lawyer, investment banker and business executive
• David Crane (Frasier), the son of Niles Crane and Daphne Moon in the sitcomFrasier

• David Crane (comic strip), created by Win Mortimer

• Crane (surname)

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