Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

DPDPE

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
DPDPE
Clinical data
Other namesL-Tyrosyl-D-penicillamyl-glycyl-L-phenylalanyl-D-penicillamine (2->5)-disulfide; H-Tyr-D-Pen(1)-Gly-Phe-D-Pen(1)-OH
Identifiers
  • (4S,7S,13S)-13-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
CAS Number
PubChemCID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC30H39N5O7S2
Molar mass645.79 g·mol−1
3D model (JSmol)
  • CC1([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SS1)(C)C)C(=O)O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)C
  • InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1
  • Key:MCMMCRYPQBNCPH-WMIMKTLMSA-N

DPDPE ([D-Pen2,D-Pen5]enkephalin) is asyntheticopioid peptide and aselectiveagonist of theδ-opioid receptor (DOR) which is used inscientific research.[1] It was developed in the early 1980s and was the first highly selective agonist of the DOR to be developed.[1] It was derived fromstructural modification ofmet-enkephalin.[2]

See also

[edit]

References

[edit]
  1. ^abTseong LF (1 September 1995).Pharmacology of Opioid Peptides. CRC Press. pp. 9–.ISBN 978-3-7186-5632-5.
  2. ^Kastin A, Kastin AJ (28 April 2011).Handbook of Biologically Active Peptides. Academic Press. pp. 1430–.ISBN 978-0-08-046379-7.


μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others


Stub icon

Thisanalgesic-related article is astub. You can help Wikipedia byadding missing information.

Retrieved from "https://en.wikipedia.org/w/index.php?title=DPDPE&oldid=1329034058"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2026 Movatter.jp