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dCMP deaminase (EC 3.5.4.12,deoxycytidylate deaminase,deoxy-CMP-deaminase,deoxycytidylate aminohydrolase,deoxycytidine monophosphate deaminase,deoxycytidine-5'-phosphate deaminase,deoxycytidine-5'-monophosphate aminohydrolase) is an enzyme which convertsdeoxycytidylic acid todeoxyuridylic acid.^[1]^[2]^[3]

References

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^Scarano E (March 1960)."The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5'-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate".The Journal of Biological Chemistry.235 (3):706–13.doi:10.1016/S0021-9258(19)67927-5.PMID 14442222.
^Scarano E, Bonaduce L (December 1960)."The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of sea urchine".The Journal of Biological Chemistry.235 (12):3556–61.doi:10.1016/S0021-9258(18)64507-7.PMID 13747062.
^Sergott RC, Debeer LJ, Bessman MJ (December 1971)."On the regulation of a bacterial deoxycytidylate deaminase".The Journal of Biological Chemistry.246 (24):7755–8.doi:10.1016/S0021-9258(19)45839-0.PMID 5002683.

External links

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dCMP+deaminase at the U.S. National Library of MedicineMedical Subject Headings (MeSH)

Purine metabolism

Anabolism

R5P→IMP:	Ribose-phosphate diphosphokinase Amidophosphoribosyltransferase Phosphoribosylglycinamide formyltransferase AIR synthetase (FGAM cyclase) Phosphoribosylaminoimidazole carboxylase Phosphoribosylaminoimidazolesuccinocarboxamide synthase IMP synthase
IMP→AMP:	Adenylosuccinate synthase Adenylosuccinate lyase reverse AMP deaminase
IMP→GMP:	IMP dehydrogenase GMP synthase reverse GMP reductase

Nucleotide salvage

Catabolism

Pyrimidine metabolism

Anabolism

CAD Carbamoyl phosphate synthase II Aspartate carbamoyltransferase Dihydroorotase
Dihydroorotate dehydrogenase Orotidine 5'-phosphate decarboxylase/Uridine monophosphate synthetase
CTP synthetase

Catabolism

Deoxyribonucleotides

v t e Hydrolases: carbon-nitrogen non-peptide (EC 3.5)
3.5.1: Linear amides / Amidohydrolases	Asparaginase Glutaminase Urease Biotinidase Aminoacylase ACY1 Aspartoacylase(ACY2) ACY3 Ceramidase Aspartylglucosaminidase Fatty acid amide hydrolase Histone deacetylase Sirtuin
3.5.2: Cyclic amides/ Amidohydrolases	Barbiturase Beta-lactamase Dihydroorotase
3.5.3: Linear amidines/ Ureohydrolases	Arginase Agmatinase Protein-arginine deiminase
3.5.4: Cyclic amidines/ Aminohydrolases	Guanine deaminase Adenosine deaminase AMP deaminase Inosine monophosphate synthase DCMP deaminase GTP cyclohydrolase I Cytidine deaminase AICDA Activation-induced cytidine deaminase
3.5.5: Nitriles/ Aminohydrolases	Nitrilase
3.5.99: Other	Riboflavinase Thiaminase II

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1Oxidoreductases (list) EC2Transferases (list) EC3Hydrolases (list) EC4Lyases (list) EC5Isomerases (list) EC6Ligases (list) EC7Translocases (list)

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