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| Clinical data | |
|---|---|
| Trade names | Deprenon, Sabiben, Sabiden |
| Other names | D-(+)-Phenylalanine; (R)-(+)-Phenylalanine; (R)-Phenylalanine;D-β-Phenylalanine; DPA;D-Phe |
| Routes of administration | By mouth |
| Drug class | Antidepressants;Enkephalinase inhibitors |
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| CAS Number | |
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| DrugBank | |
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| KEGG | |
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| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.010.549 |
| Chemical and physical data | |
| Formula | C9H11NO2 |
| Molar mass | 165.192 g·mol−1 |
| 3D model (JSmol) | |
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D-Phenylalanine (DPA,D-Phe), sold under the brand namesDeprenon,Sabiben, andSabiden, is anenantiomer ofphenylalanine which is described as anantidepressant and is marketed as aprescription drug for medical use inArgentina.[1][2] The medication has been marketed since at least the 1970s[3] and continued to be available by the 2000s.[1]
D-Phenylalanine has been found to act as anenkephalinase inhibitor, aninhibitor ofenkephalinaseenzymes that break downendogenousopioid peptides calledenkephalins.[4][5] It has been found to produceanti-inflammatory,analgesic, andanti-craving effects inanimal studies.[4][6][7][8]
D-Phenylalanine (●)D-α-Amino-β-phenylpropionic acid = (R)-α-Aminobenzenepropanoic acid S Deprenon "Promeco",D-Phenylalanine, Sabiden U Antidepressant
