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| Names | |
|---|---|
| IUPAC name Cytidine 5′-(tetrahydrogen triphosphate) | |
| Systematic IUPAC name O1-{[(2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate | |
| Other names CTP; Cytidine-5'-triphosphate | |
| Identifiers | |
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3D model (JSmol) | |
| ChemSpider |
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| ECHA InfoCard | 100.000.556 |
| MeSH | Cytidine+triphosphate |
| UNII | |
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| Properties | |
| C9H16N3O14P3 | |
| Molar mass | 483.156 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Cytidine triphosphate (CTP) is apyrimidinenucleoside triphosphate. CTP, much likeATP, consists of a ribose sugar, and three phosphate groups. The major difference between the two molecules is the base used, which in CTP iscytosine.
CTP is asubstrate in the synthesis ofRNA.
CTP is ahigh-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions.CTP is acoenzyme in metabolic reactions like the synthesis ofglycerophospholipids, where it is used for activation and transfer of diacylglycerol and lipid head groups,[1] andglycosylation of proteins.
CTP acts as an inhibitor of the enzymeaspartate carbamoyltransferase, which is used inpyrimidine biosynthesis.[2]
