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| Names | |
|---|---|
| IUPAC name 5′-Cytidylic acid | |
| Systematic IUPAC name [(2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate | |
| Other names Cytidylic acid; 5'-Cytidylic acid; Cytidine 5'-monophosphate; Cytidine 5'-phosphate; Cytidylate; 5'-CMP | |
| Identifiers | |
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3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
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| ECHA InfoCard | 100.000.506 |
| UNII | |
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| Properties | |
| C9H14N3O8P | |
| Molar mass | 323.198 g·mol−1 |
| Acidity (pKa) | 0.8, 4.5, 6.3 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Cytidine monophosphate, also known as5'-cytidylic acid or simplycytidylate, and abbreviatedCMP, is anucleotide that is used as amonomer inRNA.[1] It is anester ofphosphoric acid with thenucleosidecytidine. CMP consists of thephosphategroup, thepentosesugarribose, and thenucleobasecytosine; hence, aribonucleoside monophosphate.As asubstituent it takes the form of the prefixcytidylyl-.
CMP can be phosphorylated tocytidine diphosphate by the enzymeCMP kinase, withadenosine triphosphate orguanosine triphosphate donating the phosphate group. Sincecytidine triphosphate is generated by amination ofuridine triphosphate, the main source of CMP is from RNA being decomposed byRNAse.
