Cyclohexylamine is anorganic compound, belonging to thealiphaticamine class. It is a colorless liquid, although, like many amines, samples are often colored due to contaminants. It has a fishy odor and is miscible with water. Like other amines, it is aweak base, compared tostrong bases such asNaOH, but it is a stronger base than itsaromatic analog,aniline.
It is a useful intermediate in the production of many other organic compounds (e.g.cyclamate)
Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor tosulfenamide-based reagents used asaccelerators forvulcanization. The amine itself is an effectivecorrosion inhibitor. It has been used as a flushing aid in theprinting ink industry.[5]
It is a building block for pharmaceuticals (e.g.,mucolytics,analgesics, andbronchodilators). Most of the drugs in the following list fall into the arena of sulfonamide hypoglycemics though:
^GB2024221 idem Rudi Weyer, Volker Hitzel, Karl Geisen, Gunter Regitz,U.S. patent 4,282,239 (1981 to Hoechst Aktiengesellschaft).
^Plümpe H, Horstmann H, Puls W (March 1974). "[Isoxazolecarboxamidoalkylbenzolesulfonylurea, -semicarbazide and -aminopyrimidine as well as related compounds and their blood sugar reducing activity]".Arzneimittel-Forschung (in German).24:363–74.PMID4408067.
^Giorgio D Alo, FR2459237 (1983 to WASSERMANN SpA A).
^Dr. Walter Aumüller und Heinz Herr, DE1075588B (1960 to Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius & Brüning,).
^Kaushik D. Meisheri & Loretta A. Cipkus, WO1988008295 (to Pharmacia and Upjohn Co).
^Teramoto N (2006). "Pharmacological Profile of U-37883A, a Channel Blocker of Smooth Muscle-Type ATP-Sensitive K Channels".Cardiovascular Drug Reviews.24 (1):25–32.doi:10.1111/j.1527-3466.2006.00025.x.PMID16939631.
