 | |
| Names | |
|---|---|
| IUPAC name (RS)-2-Hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)-4H-chromen-4-one | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider |
|
| ECHA InfoCard | 100.024.931 |
| KEGG |
|
| UNII | |
| |
| |
| Properties | |
| C19H16O3 | |
| Molar mass | 292.334 g·mol−1 |
| Hazards | |
| GHS labelling: | |
   [1] | |
| Danger[1] | |
| H300,H311,H330,H360D,H372,H410[1] | |
| P201,P202,P260,P264,P270,P271,P273,P280,P281,P284,P301+P310,P302+P352,P304+P340,P308+P313,P310,P312,P314,P320,P321,P322,P330,P361,P363,P391,P403+P233,P405,P501[1] | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Coumatetralyl is ananticoagulant of the4-hydroxycoumarinvitamin K antagonist type used as arodenticide.[2]
Coumatetralyl is commonly used withgrains and othercereals as a rodent poison in conjunction with atracking powder to monitor feeding activity in a particular area. Tracking powder also clings to fur, which allows more poison to be ingested from grooming. Concentrations of the chemical are usually 500 mg per 1 kg of bait.
Symptoms of overexposure relate to failure of theblood clotting mechanism and include bleeding gums and failure of blood clotting after skin wounds. After one exposure thetoxicity of coumatetralyl is relatively low; however, if overexposure continues for several days the product becomes more toxic. The product must therefore be constantly present in the bloodstream for more than one to two days in order to be highly toxic. A single exposure, even though relatively large, may not produce toxic symptoms as the compound is quite rapidlymetabolized.
Chronic animal studies show no evidence ofcarcinogenic orteratogenic effects.
Vitamin K1 (phylloquinone) is antidotal.
