Thecords of Billroth (also known assplenic cords orred pulp cords) are found in thered pulp of thespleen between thesinusoids, consisting offibrils and connective tissue cells with a large population ofmonocytes andmacrophages. These cords contain half of the mouse body'smonocytes as a reserve so that, after tissue injury, these monocytes can move in and aid locally sourced monocytes inwound healing.^[1]

Erythrocytes pass through the cords of Billroth before entering the sinusoids. The passage into the sinusoids may be seen as a bottleneck, where erythrocytes need to be flexible in order to pass through. In disorders of erythrocyte shape and/or flexibility, such ashereditary spherocytosis, erythrocytes fail to pass through and get phagocytosed, causingextravascular hemolysis.^[2]

They are named forTheodor Billroth,Austrian surgeon.^[3]

• Anatomy Atlases – Microscopic Anatomy, plate 09.175 - "Spleen: Red Pulp"
• Histology image: 07803loa – Histology Learning System at Boston University - "Lymphoid Tissues and Organs: splenic reticulum"

• Lymphatic organ anatomy

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• Short description matches Wikidata