| 7 transmembrane receptor (metabotropic glutamate family) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | 7tm_3 | ||||||||
| Pfam | PF00003 | ||||||||
| InterPro | IPR000337 | ||||||||
| PROSITE | PDOC00754 | ||||||||
| TCDB | 9.A.14 | ||||||||
| OPM superfamily | 6 | ||||||||
| OPM protein | 4or2 | ||||||||
| CDD | cd13953 | ||||||||
| |||||||||
Theclass C G-protein-coupled receptors (InterPro: IPR000337) are a class ofG-protein coupled receptors that include themetabotropic glutamate receptors (InterPro: IPR000162) and several additional receptors.[1]
Structurally they are composed of four elements; anN-terminalsignal sequence; a large hydrophilic extracellular agonist-binding region containing several conservedcysteine residues which could be involved indisulphide bonds; a shorter region containing seven transmembrane domains; and aC-terminal cytoplasmic domain of variable length.[1] Thisprotein family includesmetabotropic glutamate receptors, the extracellularcalcium-sensing receptors, thegamma-amino-butyric acid (GABA) type B receptors, and thevomeronasal type-2 receptors.
 | Thistransmembrane receptor-related article is astub. You can help Wikipedia byexpanding it. |