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Formula | C5H7NO4S |
Molar mass | 177.17 g·mol−1 |
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Cimlanod (development codesCXL-1427 andBMS-986231) is an experimental drug for the treatment ofacute decompensated heart failure. It was discovered by Cardioxyl Pharmaceuticals, which was acquired byBristol-Myers Squibb. It is aprecursor ofnitroxyl.[1]
Cimlanod is aprodrug of CXL-1020.[2]
A preliminary study showed efficacy in patients with class III and IV heart failure.[3] A phase II clinical trial was completed in 2016.[4]
Alternative Names: BMS-986231; CXL 1427; HNO Donor
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