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Chris Goodnow | |
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Born | Hong Kong |
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Scientific career | |
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Christopher Carl Goodnow (born 19 September 1959) is an immunology researcher and the current executive director of theGarvan Institute of Medical Research. He holds the Bill and Patricia Ritchie Foundation Chair and is a Conjoint Professor in the faculty of medicine atUNSWSydney. He holds dual Australian andUScitizenship.
Born inHong Kong in 1959 to Robert Goodnow andJacqueline J. Goodnow AC, Goodnow grew up inRome andWashington DC before moving toSydney, Australia as a teenager.[1] He trained inveterinary medicine and surgery,immunochemistry andimmunology at theUniversity of Sydney and inDNA technology atStanford University. After doctoral studies atMelbourne'sWalter and Eliza Hall Institute of Medical Research and the University of Sydney, he joined the faculty of the Stanford University Medical School and theHoward Hughes Medical Institute in 1990.[2] There he established the concept of multiple immune tolerance checkpoints, a framework now widely used in cancer treatment with "checkpoint inhibitors", and revealed the function of key genes in these checkpoints.[3]
In 1997 Goodnow joined the faculty at theAustralian National University as professor and founding director of the Medical Genome Centre, leading its development into a major national research facility, the Australian Phenomics Facility. In 2015 he joined theGarvan Institute of Medical Research as deputy director to translate genomic DNA sequence analysis of the human immune system into understanding the cause of immune disorders and developing more effective, personalised treatments.[2] During this period Goodnow oversaw the development of the Garvan-Weizmann Centre for Cellular Genomics in partnership with theWeizmann Institute of Science in Israel,[4][5] the only multidisciplinary centre of its kind in thesouthern hemisphere as well as playing a key role in the development of the Clinical Immunogenomics Research Consortium Australia (CIRCA).[6] In May 2018, Goodnow was named Executive Director of the Garvan Institute.[7]
Goodnow is well known for leading a 1980 expedition to Indonesia's remoteMentawai Islands off the coast ofSumatra, discovering the now-famous surf breaks and a wave that is today considered one of the world's best, Macaronis.[20][21][22][23]