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Chlorquinaldol

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Chlorquinaldol
Names

Preferred IUPAC name 5,7-Dichloro-2-methylquinolin-8-ol
Other names Anginazol; Lacoid, Nerisone
Identifiers
CAS Number	72-80-0^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:74500^N
ChEMBL	ChEMBL224325^Y
ChemSpider	6062^Y
ECHA InfoCard	100.000.718
KEGG	D07208^Y
PubChem CID	6301
UNII	D6VHC87LLS^Y
CompTox Dashboard(EPA)	DTXSID3048998
InChI InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3^Y Key: GPTXWRGISTZRIO-UHFFFAOYSA-N^Y InChI=1/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3 Key: GPTXWRGISTZRIO-UHFFFAOYAU
SMILES Clc1c(O)c2nc(ccc2c(Cl)c1)C
Properties
Chemical formula	C₁₀H₇Cl₂NO
Molar mass	228.07 g/mol
Pharmacology
ATC code	D08AH02 (WHO) G01AC03 (WHO),P01AA04 (WHO),R02AA11 (WHO)
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Chemical compound

Chlorquinaldol is anantimicrobial agent and antiseptic.^[1] It is achlorinated derivative of the popular chelating agent8-hydroxyquinoline. It is applied topically as a cream and internally as alosenge.^[2]

It was marketed byGeigy as an intestinal antiseptic andamebicide with the trade nameSiosteran.^{[citation needed]}

^Mett H, Gyr K, Zak O, Vosbeck K (July 1984)."Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial drugs".Antimicrob. Agents Chemother.26 (1):35–8.doi:10.1128/aac.26.1.35.PMC 179912.PMID 6236746.
^Kutscher, Bernhard (2020). "Dermatologicals ( D ), 4. Antiseptics and Disinfectants ( D 08), Anti‐Acne Preparations ( D 10), and Other Dermatological Preparations ( D 11)".Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. pp. 1–22.doi:10.1002/14356007.w08_w03.ISBN 978-3-527-30673-2.

v t e Antiseptics anddisinfectants (D08)
Acridine derivatives	Ethacridine lactate 9-Aminoacridine Euflavine
Biguanides andamidines	Dibrompropamidine Chlorhexidine^# Propamidine Hexamidine Polihexanide
Phenol and derivatives	Hexachlorophene Policresulen Phenol Triclosan Triclocarban Chloroxylenol^# Biphenylol Fenticlor
Nitrofuran derivatives	Nitrofurazone
Iodine products	Iodine/octylphenoxypolyglycolether Povidone-iodine^# Diiodohydroxypropane
Quinoline derivatives	Dequalinium Chlorquinaldol Oxyquinoline Clioquinol
Quaternary ammonium compounds	Benzalkonium Benzethonium chloride Cetrimonium (bromide/chloride) Cetylpyridinium Cetrimide Benzoxonium chloride Didecyldimethylammonium chloride
Mercurial products	Mercuric amidochloride Phenylmercuric borate Mercuric chloride Merbromin Nitromersol Thiomersal Mercuric iodide
Silver compounds	Silver nitrate
Alcohols	Propanol (propyl alcohol) Isopropanol (isopropyl alcohol) Ethanol (ethyl alcohol)^#
Other	Potassium permanganate Sodium hypochlorite Halazone Monalazone Hydrogen peroxide Eosin Chloramine-T (tosylchloramide) Octenidine dihydrochloride
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Arsenic compounds

Quinoline derivatives

Imidazoles	Metronidazole Clotrimazole Miconazole Econazole Ornidazole Isoconazole Tioconazole Ketoconazole Fenticonazole Azanidazole Propenidazole Butoconazole Omoconazole Oxiconazole Flutrimazole
Triazoles	Terconazole
Polyenes	Nystatin Natamycin Amphotericin B
Other	Ciclopirox Methylrosaniline

Other

Nitroimidazole derivatives	Metronidazole^# Tinidazole Ornidazole Nimorazole Secnidazole Azanidazole Propenidazole
Other	isoquinoline (Emetine/Dehydroemetine)

Hydroxyquinoline derivatives	Cl (Chlorquinaldol) Br (Tilbroquinol Broxyquinoline) I (Diiodohydroxyquinoline) I, Cl (Clioquinol) related:Chiniofon
Dichloroacetamide derivatives	Diloxanide^# Clefamide Etofamide Teclozan
Aminoglycoside	Paromomycin^#

Other/ungrouped

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