| Clinical data | |
|---|---|
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| ATC code | |
| Pharmacokinetic data | |
| Excretion | urine |
| Identifiers | |
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| CAS Number | |
| PubChemCID | |
| ChemSpider | |
| UNII |
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| KEGG | |
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| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.002.902 |
| Chemical and physical data | |
| Formula | C10H12ClNO4 |
| Molar mass | 245.66 g·mol−1 |
| 3D model (JSmol) | |
| Melting point | 86 to 92 °C (187 to 198 °F) |
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Chlorphenesin carbamate (Maolate,Musil) is a centrally actingmuscle relaxant used to treat muscle pain andspasms.[1][2] Chlorphenesin carbamate is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such asbenzodiazepines.
Other central effects include sedation,anxiolysis, and dizziness.
A related chemical, chlorphenesin (C9H11ClO3)without thecarbamate group, is used as a preservative in products such as cosmetics. It hasantifungal and someantibacterial properties, and is classified as an antifungal for topical use by the WHO.[3]
The major adverse effect from this preservative on skin isallergic contact sensitivity.[4][5] Systemic intoxication fromtransdermal use has not been observed, although the FDA discourages its use as an ingredient in nipple cream for nursing mothers.[6]