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| Clinical data | |
|---|---|
| Other names | 4-Chlordehydromethyltestosterone; Dehydrochloromethyltestosterone; 4-Chloromethandienone |
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| Routes of administration | By mouth |
| Drug class | Androgen;anabolic steroid |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Bioavailability | High |
| Metabolism | Liver |
| Eliminationhalf-life | 16 hours[citation needed] |
| Excretion | Urine |
| Identifiers | |
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| CAS Number | |
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| ChemSpider |
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| UNII | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.392.451 |
| Chemical and physical data | |
| Formula | C20H27ClO2 |
| Molar mass | 334.88 g·mol−1 |
| 3D model (JSmol) | |
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Chlorodehydromethyltestosterone (CDMT; brand nameOral Turinabol), also known as4-chloro-17β-hydroxy17α-methylandrosta-1,4-dien-3-one, is ananabolic–androgenic steroid (AAS). It is the 4-chloro-substitutedderivative ofmetandienone (dehydromethyltestosterone).
CDMT was the first original product ofJenapharm, anEast Germanpharmaceutical company. It was patented in 1961. The idea of combining the structures of4-chlorotestosterone (clostebol) and metandienone originated with chemist Albert Stachowiak.[citation needed] At the time, this represented a unique dissociation ofanabolic fromandrogenic effects after oral administration.[clarification needed][2] The product was introduced for clinical use in 1965 and remained in use until 1994, when production was discontinued.[citation needed]
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CDMT was the key steroid administered to approximately ten thousand East German athletes as part of a secret doping program, known asState Plan Topic 14.25, often without them knowing the nature of the "vitamins" they were forced to take. The program remained in place from about 1968 until the collapse of the German Democratic Republic in 1989. In the 1990s, Franke and Berendonk examined GDR archives to elucidate the expansive scope of this operation, which had resulted in numerous medal wins and world-record performances.[3]
Following allegations[by whom?] of widespread doping, theInternational Olympic Committee reanalyzed samples from theBeijing 2008 andLondon 2012 Olympic Games using thespectrometric method developed byGrigory Rodchenkov in 2011[4] for detecting long-lasting metabolites of CDMT. Weightlifters andsprinters in particular were found to have used CDMT.
In August 2017,UFC Light Heavyweight ChampionJon Jones tested positive for turinabol following his victory overDaniel Cormier atUFC 214 the month prior.[5]
Colorado Rockies third basemanColton Welker tested positive in May 2021 while playing for theTriple-AAlbuquerque Isotopes. He was suspended for eighty games.[6]