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| Trade names | Naxcel |
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| Formula | C19H17N5O7S3 |
| Molar mass | 523.55 g·mol−1 |
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Ceftiofur is anantibiotic of thecephalosporin type (third generation), licensed for use inveterinary medicine. It was first described in 1987.[3] It is marketed bypharmaceutical companyZoetis asExcenel,[4] Naxcel, and Excede and is also the active ingredient in that company's Spectramast LC (lactating cow formulation) and Spectramast DC (dry cow formulation) product.[citation needed]
It is resistant to theantibiotic resistance enzymebeta-lactamase, and has activity against bothGram-positive andGram-negative bacteria.Escherichia coli strains resistant to ceftiofur have been reported.[5]
The metabolite desfuroylceftiofur also has antibiotic activity.[6] The two compounds are measured together to measure for antibiotic activity in milk (alongside other antibiotics).[7]
