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Carbonic anhydrase 13

From Wikipedia, the free encyclopedia
Human protein
CA13
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

3CZV,3D0N,3DA2,4HU1,4KNM,4KNN,4QIZ,4QJP,4QJX,4QSJ

Identifiers
AliasesCA13, CAXIII, carbonic anhydrase 13
External IDsOMIM:611436;MGI:1931322;HomoloGene:75207;GeneCards:CA13;OMA:CA13 - orthologs
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for CA13
Genomic location for CA13
Band8q21.2Start85,220,587bp[1]
End85,284,073bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for CA13
Genomic location for CA13
Band3|3 A1Start14,706,787bp[2]
End14,728,062bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • jejunal mucosa

  • palpebral conjunctiva

  • pancreatic epithelial cell

  • mucosa of ileum

  • nasal epithelium

  • amniotic fluid

  • endothelial cell

  • gingival epithelium

  • skin of arm

  • duodenum
Top expressed in
  • meninges

  • esophagus

  • membranous bone

  • lip

  • jejunum

  • mandible

  • vestibular sensory epithelium

  • vestibular membrane of cochlear duct

  • gastric mucosa

  • epithelium of stomach
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

377677

71934

Ensembl

ENSG00000185015

ENSMUSG00000027555

UniProt

Q8N1Q1

Q9D6N1

RefSeq (mRNA)

NM_198584

NM_024495

RefSeq (protein)

NP_940986

NP_078771

Location (UCSC)Chr 8: 85.22 – 85.28 MbChr 3: 14.71 – 14.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Carbonic anhydrase 13 is aprotein that in humans is encoded by theCA13gene.[5]

Function

[edit]

Carbonic anhydrases (CAs) are a family ofzincmetalloenzymes thatcatalyze the interconversion betweencarbon dioxide andwater and thedissociated ions ofcarbonic acid (i.e.bicarbonate andhydrogen ions).[6][7]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000185015 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000027555 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"Entrez Gene: Carbonic anhydrase 13". Retrieved2019-12-31.
  6. ^Badger MR, Price GD (1994). "The role of carbonic anhydrase in photosynthesis".Annu. Rev. Plant Physiol. Plant Mol. Biol.45:369–392.doi:10.1146/annurev.pp.45.060194.002101.
  7. ^Lindskog S (1997). "Structure and mechanism of carbonic anhydrase".Pharmacology & Therapeutics.74 (1):1–20.doi:10.1016/S0163-7258(96)00198-2.PMID 9336012.

Further reading

[edit]

External links

[edit]
  • Overview of all the structural information available in thePDB forUniProt:Q8N1Q1 (Human Carbonic anhydrase 13) at thePDBe-KB.
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This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

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