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Carbocromen

From Wikipedia, the free encyclopedia

Vasodilator

Pharmaceutical compound

Carbocromen
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	C01DX05 (WHO)
Identifiers
IUPAC name ethyl 2-({3-[2-(diethylamino)ethyl]-4-methyl-2-oxo-2H-chromen-7-yl}oxy)acetate
CAS Number	804-10-4^N
PubChemCID	12604
ChemSpider	12084^Y
UNII	R0C9NIE5JJ
ChEMBL	ChEMBL163672^Y
CompTox Dashboard(EPA)	DTXSID60230301
ECHA InfoCard	100.011.233
Chemical and physical data
Formula	C₂₀H₂₇NO₅
Molar mass	361.438 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(OCC)COc2ccc\1c(OC(=O)/C(=C/1C)CCN(CC)CC)c2
InChI InChI=1S/C20H27NO5/c1-5-21(6-2)11-10-17-14(4)16-9-8-15(12-18(16)26-20(17)23)25-13-19(22)24-7-3/h8-9,12H,5-7,10-11,13H2,1-4H3^Y Key:KLOIYEQEVSIOOO-UHFFFAOYSA-N^Y
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Carbocromen (chromonar) is avasodilator.^[1]^[2] It was used as a coronary dilator between 1963 and 1966.^[3]

^"Carbocromen".AdisInsight. Springer.
^Chekman IS, Kazak LI (1976). "[Biochemical mechanisms of action of coronarodilating agents (review of the literature)]".Vrachebnoe Delo (in Russian) (5):23–29.PMID 9729.
^Entry onCarbocromen. at:Römpp Online. Georg Thieme Verlag, retrieved 2017-08-16.

v t e Vasodilators used incardiac diseases (C01D)
Nitrovasodilators	Nitroglycerin # Isosorbide dinitrate # Isosorbide mononitrate Itramin tosilate Linsidomine Molsidomine Nicorandil Pentaerythritol tetranitrate Propatylnitrate Tenitramine Trolnitrate
Quinolone vasodilators	Flosequinan^‡
Others	Benziodarone Carbocromen Cinepazet Cloridarol Dilazep Efloxate Etafenone Gapicomine Heptaminol Hexobendine Imolamine Levosimendan Nesiritide Nicorandil Oxyfedrine Pimobendan Prenylamine Serelaxin Trapidil Vericiguat
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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