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| ECHA InfoCard | 100.236.933 |
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| Formula | C19H26O2 |
| Molar mass | 286.415 g·mol−1 |
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Cannabidivarin (CBDV,GWP42006) is a non-intoxicatingpsychoactivecannabinoid found inCannabis. It is ahomolog (chemistry) ofcannabidiol (CBD), with theside-chain shortened by twomethylene bridges (CH2 units).
Although cannabidivarin (CBDV) is usually a minor constituent of the cannabinoid profile, enhanced levels of CBDV have been reported in feral populations ofC. indica ( =C. sativa ssp.indica var.kafiristanica) from northwestIndia, and inhashish fromNepal.[1][2][3]
CBDV demonstrated anticonvulsant in rodent models in a single published study.[4] It was identified for the first time in 1969 by Vollner et al.[5]
Similarly to CBD, it has seven double bond isomers and 30 stereoisomers (see:Cannabidiol#Isomerism). It is not scheduled byConvention on Psychotropic Substances. It is being actively developed byGW Pharmaceuticals (as GWP42006)[6] because of a demonstrated neurochemical pathway for previously observed anti-epileptic and anti-convulsive action.[7] GW has begun several Phase-2 trials for adultepilepsy,[8] for childhood epilepsy and for Prader-Willi Syndrome.[9][10]
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