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Names | |
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Preferred IUPAC name (8E,10E,12Z)-Octadeca-8,10,12-trienoic acid | |
Other names
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Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChemSpider |
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UNII | |
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Properties | |
C18H30O2 | |
Molar mass | 278.436 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). |
Calendic acid (sometimesα-calendic acid) is anunsaturated fatty acid, named for thepot marigold (Calendula officinalis), from which it is obtained. It is chemically similar to theconjugated linoleic acids; laboratory work suggests it may have similarin vitro bioactivities.[1]
Calendic acid is anomega-6 fatty acid.[2] though not usually listed with this group. Calendic acid is synthesised inCalendula officinalis fromlinoleate by an unusual Δ12-oleatedesaturase (a FAD 2 variant) that converts thecis-double bond at position 9 to atrans,trans-conjugated double bond system.[3] Anall-trans beta isomer has been described.[1]
Calendic acid is the fatty acid responsible for the reduction in feed intake and improved feed utilization in mice when calendula oil is added to the feedstuff, as demonstrated by the comparative experiments in the examples using corn oil.[4]