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CUMYL-PINACA

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
CUMYL-PINACA
Legal status
Legal status
Identifiers
  • 1-pentyl-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC22H27N3O
Molar mass349.478 g·mol−1
3D model (JSmol)
  • CCCCCN1N=C(C(=O)NC(C)(C)C2=CC=CC=C2)C2=CC=CC=C12
  • InChI=1S/C22H27N3O/c1-4-5-11-16-25-19-15-10-9-14-18(19)20(24-25)21(26)23-22(2,3)17-12-7-6-8-13-17/h6-10,12-15H,4-5,11,16H2,1-3H3,(H,23,26)
  • Key:LCBASRYREGWIJT-UHFFFAOYSA-N

CUMYL-PINACA (also known asSGT-24) is anindazole-3-carboxamide basedsynthetic cannabinoid. CUMYL-PINACA acts as a potentagonist for thecannabinoid receptors, with approximately 3x selectivity forCB1, having an EC50 of 0.15nM for humanCB1 receptors and 0.41nM for humanCB2 receptors.[1] In its pure form, it is described as a sticky oil which can cause poisoning throughtransdermal exposure.[2]

Legal status

[edit]

Sweden's public health agency suggested classifying CUMYL-PINACA as a hazardous substance, on November 10, 2014.[3]

See also

[edit]

References

[edit]
  1. ^Bowden; et al. (11 April 2013)."Patent WO 2014167530 - Cannabinoid compounds".New Zealand Patent application 623626. Retrieved11 July 2015.
  2. ^Dobaja M, Grenc D, Kozelj G, Brvar M (March 2017). "Occupational transdermal poisoning with synthetic cannabinoid cumyl-PINACA".Clinical Toxicology.55 (3):193–195.doi:10.1080/15563650.2016.1278224.PMID 28084855.S2CID 21304629.
  3. ^"Cannabinoider föreslås bli klassade som hälsofarlig vara". Retrieved11 July 2015.
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