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| Formula | C22H25NO3 |
| Molar mass | 351.446 g·mol−1 |
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CS-27349, orL-2-α-tropinyl benzilate, is an experimentalincapacitating agent. It acts as anantagonist tomuscarinic acetylcholine receptors, causingdelirium. It has 37% of the potency of the related compound3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ.[1] It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then.[2]
It is interesting to notice that 2-tropinone is made fromcocaine alkaloid.[5] On a related note, it is worthy of mention that 2-tropinone has also had use in the synthesis ofisohomoepibatidine andisohomoepiboxidine.[6][7] These are neonicotinoids that were explored as alternatives to epibatidine, which was too toxic for clinical use.
