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CHTF18

From Wikipedia, the free encyclopedia
Protein-coding gene in humans
CHTF18
Identifiers
AliasesCHTF18, C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL, chromosome transmission fidelity factor 18
External IDsOMIM:613201;MGI:2384887;HomoloGene:32532;GeneCards:CHTF18;OMA:CHTF18 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for CHTF18
Genomic location for CHTF18
Band16p13.3Start788,046bp[1]
End800,737bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for CHTF18
Genomic location for CHTF18
Band17|17 A3.3Start25,937,900bp[2]
End25,946,393bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right testis

  • left testis

  • mucosa of transverse colon

  • right hemisphere of cerebellum

  • pancreatic ductal cell

  • gonad

  • sural nerve

  • ventricular zone

  • ganglionic eminence

  • granulocyte
Top expressed in
  • epiblast

  • yolk sac

  • internal carotid artery

  • external carotid artery

  • morula

  • embryo

  • blastocyst

  • embryo

  • ventricular zone

  • neural layer of retina
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

63922

214901

Ensembl

ENSG00000127586

ENSMUSG00000019214

UniProt

Q8WVB6

Q8BIW9

RefSeq (mRNA)

NM_022092

NM_145409

RefSeq (protein)

NP_071375

NP_663384

Location (UCSC)Chr 16: 0.79 – 0.8 MbChr 17: 25.94 – 25.95 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chromosome transmission fidelity protein 18 homolog is aprotein that in humans is encoded by theCHTF18gene.[5][6]

Interactions

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CHTF18 has been shown tointeract with:

References

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  1. ^abcGRCh38: Ensembl release 89: ENSG00000127586 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000019214 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^abOhta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T (Oct 2002)."A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein".The Journal of Biological Chemistry.277 (43):40362–7.doi:10.1074/jbc.M206194200.PMID 12171929.
  6. ^"Entrez Gene: CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)".
  7. ^abcdeBermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J (Sep 2003)."The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA".Proceedings of the National Academy of Sciences of the United States of America.100 (18):10237–42.Bibcode:2003PNAS..10010237B.doi:10.1073/pnas.1434308100.PMC 193545.PMID 12930902.
  8. ^abcMerkle CJ, Karnitz LM, Henry-Sánchez JT, Chen J (Aug 2003)."Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment".The Journal of Biological Chemistry.278 (32):30051–6.doi:10.1074/jbc.M211591200.PMID 12766176.

External links

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Further reading

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