This gene is a member of thecadherin superfamily of genes, encoding calcium-dependent intercellular adhesionglycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed inmyoblasts and upregulated inmyotubule-forming cells. The protein is thought to be essential for the control ofmorphogenetic processes, specificallymyogenesis, and may provide a trigger for terminal muscle cell differentiation.[6]
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (December 1992). "The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species".Genomics.14 (2):488–90.doi:10.1016/S0888-7543(05)80247-2.PMID1427864.
^Kaufmann U, Zuppinger C, Waibler Z, Rudiger M, Urbich C, Martin B, Jockusch BM, Eppenberger H, Starzinski-Powitz A (November 2000). "The armadillo repeat region targets ARVCF to cadherin-based cellular junctions".J. Cell Sci.113 (22):4121–35.doi:10.1242/jcs.113.22.4121.PMID11058098.
Kuch C, Winnekendonk D, Butz S, Unvericht U, Kemler R, Starzinski-Powitz A (1997). "M-cadherin-mediated cell adhesion and complex formation with the catenins in myogenic mouse cells".Exp. Cell Res.232 (2):331–8.doi:10.1006/excr.1997.3519.PMID9168809.
Kremmidiotis G, Baker E, Crawford J, Eyre HJ, Nahmias J, Callen DF (1998). "Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity".Genomics.49 (3):467–71.doi:10.1006/geno.1998.5281.PMID9615235.
Kaufmann U, Zuppinger C, Waibler Z, Rudiger M, Urbich C, Martin B, Jockusch BM, Eppenberger H, Starzinski-Powitz A (2001). "The armadillo repeat region targets ARVCF to cadherin-based cellular junctions".J. Cell Sci.113 (22):4121–35.doi:10.1242/jcs.113.22.4121.PMID11058098.
