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CD3G

From Wikipedia, the free encyclopedia

Protein-coding gene in humans
CD3G
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

1SY6

Identifiers
AliasesCD3G, CD3-GAMMA, IMD17, T3G, CD3g molecule, CD3GAMMA, CD3 gamma subunit of T-cell receptor complex
External IDsOMIM:186740;MGI:88333;HomoloGene:55;GeneCards:CD3G;OMA:CD3G - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for CD3G
Genomic location for CD3G
Band11q23.3Start118,344,344bp[1]
End118,355,161bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for CD3G
Genomic location for CD3G
Band9 A5.2|9 24.84 cMStart44,880,870bp[2]
End44,891,729bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • buccal mucosa cell

  • lymph node

  • thymus

  • granulocyte

  • blood

  • appendix

  • epithelium of colon

  • superficial temporal artery

  • testicle

  • bone marrow cells
Top expressed in
  • thymus

  • mesenteric lymph nodes

  • superior surface of tongue

  • gallbladder

  • blood

  • spleen

  • ankle joint

  • subcutaneous adipose tissue

  • duodenum

  • jejunum
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

917

12502

Ensembl

ENSG00000160654

ENSMUSG00000002033

UniProt

P09693

P11942

RefSeq (mRNA)

NM_000073

NM_009850

RefSeq (protein)

NP_000064

NP_033980

Location (UCSC)Chr 11: 118.34 – 118.36 MbChr 9: 44.88 – 44.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

T-cell surface glycoprotein CD3 gamma chain is aprotein that in humans is encoded by theCD3Ggene.

T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000160654Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000002033Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"Entrez Gene: CD3G CD3g molecule, gamma (CD3-TCR complex)".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

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