| chemokine (C-C motif) ligand 14 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CCL14 | ||||||
| Alt. symbols | SCYA14, HCC-1, HCC-3, NCC-2, SCYL2, CKb1, MCIF | ||||||
| NCBI gene | 6358 | ||||||
| HGNC | 10612 | ||||||
| OMIM | 601392 | ||||||
| RefSeq | NM_032962 | ||||||
| UniProt | Q16627 | ||||||
| Other data | |||||||
| Locus | Chr. 17q11.2 | ||||||
| |||||||
Chemokine (C-C motif) ligand 14 (CCL14) is a smallcytokine belonging to the CCchemokine family. It is also commonly known as HCC-1. It is produced as aprotein precursor that is processed to generate a mature activeprotein containing 74amino acids that and is 46% identical in amino acid composition toCCL3 andCCL4. This chemokine is expressed in various tissues includingspleen,bone marrow,liver,muscle, andgut.[1] CCL14 activatesmonocytes, but does not induce theirchemotaxis. Human CCL14 is located onchromosome 17 within a cluster of other chemokines belonging to the CC family.[2]
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