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Butixocort

From Wikipedia, the free encyclopedia
Chemical compound

Pharmaceutical compound
Butixocort
Clinical data
Other namesTixocortol butyrate; Tixocortol 17-butyrate; 11β,17α-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione 17-butyrate; JO-1717
Drug classCorticosteroid;Glucocorticoid
Identifiers
  • [(8S,9S,10R,11S,13S,14S,17R)-11-Hydroxy-10,13-dimethyl-3-oxo-17-(2-sulfanylacetyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC25H36O5S
Molar mass448.62 g·mol−1
3D model (JSmol)
  • CCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)CS
  • InChI=1S/C25H36O5S/c1-4-5-21(29)30-25(20(28)14-31)11-9-18-17-7-6-15-12-16(26)8-10-23(15,2)22(17)19(27)13-24(18,25)3/h12,17-19,22,27,31H,4-11,13-14H2,1-3H3/t17-,18-,19-,22+,23-,24-,25-/m0/s1
  • Key:HOAKOHHSHOCDLI-TUFAYURCSA-N

Butixocort, also known astixocortol butyrate, is asyntheticglucocorticoidcorticosteroid.[1][2]

References

[edit]
  1. ^William Andrew Publishing (22 October 2013).Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 769–.ISBN 978-0-8155-1856-3.
  2. ^Belvisi MG, Hele DJ (2003). "Soft steroids: a new approach to the treatment of inflammatory airways diseases".Pulmonary Pharmacology & Therapeutics.16 (6):321–5.doi:10.1016/S1094-5539(03)00105-6.PMID 14580922.


GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others


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