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| Other names | n-butylp-aminobenzoate |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Routes of administration | Topical |
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| ECHA InfoCard | 100.002.107 |
| Chemical and physical data | |
| Formula | C11H15NO2 |
| Molar mass | 193.246 g·mol−1 |
| 3D model (JSmol) | |
| Melting point | 58 °C (136 °F) |
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Butamben is alocal anesthetic. Proprietary names includes Alvogil in Spain and Alvogyl in Switzerland. It is one of three components in the topical anestheticCetacaine.
It is theester of4-aminobenzoic acid andbutanol.[1] A white, odourless, crystalline powder. that is mildly soluble in water (1 part in 7000) and soluble in alcohol, ether, chloroform, fixed oils, and dilute acids. It slowly hydrolyses when boiled with water. Synonyms include Butamben, Butilaminobenzoato, and Butoforme.
TheFischer esterification of4-Nitrobenzoic acid [62-23-7] (1) and1-Butanol [71-36-3] (2) gives n-Butyl 4-Nitrobenzoate [120-48-9] (3).Bechamp reduction then gives Butamben (4).
Alternatively,4-aminobenzoic acid can be used directly.
