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BioLineRx

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BioLineRx Ltd.
Company typePublic
NasdaqBLRX
TASEBLRX
IndustryBiotechnology
Founded2003; 22 years ago (2003)
Headquarters,
Israel
Key people
Philip Serlin (CEO)
ServicesDrug development
OwnersNovartis (12.8%, 2014)
Websitewww.biolinerx.com
Footnotes / references
[1][2]
BioLineRX office inHar Hotzvim Technology Park, Jerusalem

BioLineRx Ltd. (Hebrew:ביוליין אר אקס), orBioLine, is apublicly traded drug development company. Headquartered in Israel, its shares are traded on theNASDAQ Capital Market and on theTel Aviv Stock Exchange.

Corporate history

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The firm was established in 2003 as a joint venture ofTeva, Hadasit Bio-Holdings, theJerusalem Development Authority, Yehuda Zisapel, and other investors.[3] It executed aninitial public offering on the Tel Aviv Stock Exchange in February 2007, raising 211 millionNIS ($50 million) – the TASE's largest biotech IPO until that time.[4][5] In July 2011 BioLine'sADRs began trading on the NASDAQ Capital Market.[6][7] In January 2012, the firm announced a deal with Genoscience, a French pharmaceutical company to jointly develop and market the BL-8020 compound, as a treatment forHepatitis C.[8] At the end of 2014,Novartis acquired a 12.8%stake in the company as a strategic move to gain access to Israeli-sourced drug candidates.[2]

Management

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Morris Laster, (M.D.) an alumnus of.Downstate Medical Center, wasCEO of BioLineRx until 2009. He was replaced by Kinneret Savitsky, alumnus ofTel Aviv University early in 2010.[9] Savitsky was replaced as CEO by BioLine COO Philip Serlin on October 10, 2016.

Operations

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Previous logo

BioLineRx is a drug development company When promising compounds are discovered, the firm leads them throughpreclinical trials and engages other companies to further develop them into commercializable drugs.[10] The company entered into its first major commercialization agreement in 2009 when it partnered with Ikaria Holdings Inc. to develop its BL-1040 compound.[11] In 2010, BioLine entered into a commercialization agreement with Cypress Bioscience Inc. for development of its BL-1020 compound. The agreement with Cypress was canceled in 2011 when the company was taken over byRamius LLC.[12]

Pipeline

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Below is a partial list of drug compounds in various stages ofdevelopment byBioLineRx. Unless indicated otherwise, they have not obtained regulatory approval in relation to the diseases cited.

See also

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References

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  1. ^"BLRX Profile: BioLineRx Ltd. Stock".Yahoo! Finance. 2011. Retrieved28 November 2011.
  2. ^ab"Novartis Makes $10M Investment in BioLineRx". Industry Watch.Genetic Engineering & Biotechnology News. Vol. 35, no. 2. 16 December 2014. p. 9.
  3. ^Grayeff, Yigal (13 January 2005)."BioLineRx signs 3 deals to develop drugs".The Jerusalem Post. Archived fromthe original on 3 February 2010. Retrieved28 November 2011 – viaIVC Research Center.
  4. ^Cohen, Omri (7 February 2007)."Biotech comes of age: Bioline floats at half-billion shekel market cap".TheMarker. Retrieved28 November 2011.Bioline Therapeutics today pulled off its initial public offering in Tel Aviv, raising NIS 211 million at a company valuation of NIS 494 million, making this the biggest flotation by a biotechnology company in local history.
  5. ^Rheinheimer, Laura (8 February 2007)."BioLineRx raises $50m. in TASE's largest biomedical IPO".The Jerusalem Post. Retrieved28 November 2011.BioLineRx Ltd. on Wednesday priced the largest ever initial public offering of a biomedical company on the Tel Aviv Stock Exchange, raising a total of NIS 211 million, or $50m.
  6. ^"BioLineRx ADRs Begin Trading on NASDAQ". 25 July 2011. Retrieved27 April 2019.
  7. ^Cohen, Tova (24 July 2011). Magnowski, Daniel (ed.)."BioLineRX ADRs to begin trading on Nasdaq Monday".Reuters.Archived from the original on 24 September 2015. Retrieved30 June 2017.
  8. ^Wang, Lu (24 January 2012)."Achillion, BioLineRx, J&J Snack, Rubicon: U.S. Equity Movers". Bloomberg News. Archived fromthe original on 24 January 2012.
  9. ^"Kinneret Livnat Savitsky Ph.D.: Executive Profile & Biography".Bloomberg Business. Retrieved21 February 2015.
  10. ^Brinn, David (3 June 2007)."BioLineRx—Israel's biotech supermarket".ISRAEL21c. Archived fromthe original on 5 April 2012. Retrieved28 November 2011.
  11. ^Habib-Valdhorn, Shiri (28 April 2010)."BiolineRX earns $10m milestone payment".Globes. Archived fromthe original on 3 August 2012. Retrieved28 November 2011.
  12. ^Weinreb, Gali (11 May 2011)."BiolineRX and Cypress cancel schizophrenia drug agreement".Globes. Archived fromthe original on 15 June 2011. Retrieved28 November 2011.
  13. ^"BioLineRx In-Licenses Novel Compound for Treatment of Neuropathic Pain". Archived fromthe original on 2015-09-26.
  14. ^"Israeli co to hold clinical trial for treatment of Schizophrenia in India".The Hindu Business Line.Jerusalem. 24 November 2011. Retrieved28 November 2011.
  15. ^BioLineRx (13 September 2011)."BioLineRx Announces Positive Preliminary Results from Phase I Clinical Trial of BL-1021 for Neuropathic Pain" (Press release).Jerusalem. Retrieved28 November 2011 – viaBusiness Wire.
  16. ^"Bioline looks to heart attack treatment clinical trial".Globes. 27 February 2011. Archived fromthe original on 3 August 2012. Retrieved28 November 2011.
  17. ^"US company buys exclusive license for Israeli heart attack drug for $285 million".Israel21c. 8 July 2009. Retrieved28 November 2011.
  18. ^"Other".www.biolinerx.com. Archived fromthe original on 2016-12-02.
  19. ^Wrobel, Sharon (15 September 2011)."Bioline RX Gets European Device Confirmation for Bl-5010 Drug".Bloomberg. Retrieved28 November 2011.
  20. ^"BioLineRx has acquired the rights to compound BL-7040 from Yissum and Prof. Soreq".The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences. 27 June 2011. Archived fromthe original on 12 July 2011. Retrieved28 November 2011.
  21. ^"BioLineRx signs pact with Genoscience & RFS Pharma to develop and commercialize BL-8030 to treat hepatitis C".Pharmabiz.com.Jerusalem, Israel. 8 February 2012. Archived fromthe original on 21 February 2015. Retrieved8 February 2012.

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