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| Routes of administration | Oral |
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| ECHA InfoCard | 100.035.744 |
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| Formula | C31H32N4O2 |
| Molar mass | 492.623 g·mol−1 |
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Bezitramide is an opioidanalgesic. Bezitramide itself is aprodrug which is readilyhydrolyzed in thegastrointestinal tract to itsactive metabolite, despropionyl-bezitramide.[2] Bezitramide was discovered atJanssen Pharmaceutica in 1961.[3][4][5] It is most commonly marketed under the trade nameBurgodin.
The drug was pulled from the shelves in theNetherlands in 2004 after fatal overdose cases, including one where a five-year-old child took one tablet from his mother's purse, ate it, and promptly died.[6]
Bezitramide is regulated much the same asmorphine in all known jurisdictions and is aSchedule II substance under the United States' Controlled Substances Act of 1970, with an ACSCN of 9800 and zero annual manufacturing quota.[7] However, as of May 2021, it has never been marketed in the United States.
