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Benziodarone

From Wikipedia, the free encyclopedia

Chemical compound

Pharmaceutical compound

Benziodarone
Clinical data


ATC code	C01DX04 (WHO)
Identifiers
IUPAC name 4-[(2-ethyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenol
CAS Number	68-90-6^N
PubChemCID	6237
ChemSpider	6001^Y
UNII	75CL65GTYR
ChEMBL	ChEMBL232201^Y
CompTox Dashboard(EPA)	DTXSID1046134
ECHA InfoCard	100.000.632
Chemical and physical data
Formula	C₁₇H₁₂I₂O₃
Molar mass	518.089 g·mol⁻¹
InChI InChI=1S/C17H12I2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3^Y Key:CZCHIEJNWPNBDE-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Benziodarone is avasodilator.

Benziodaron synthesis:U.S. patent 3,012,042

Bufeniode has the same aromatic substitution pattern.

See also

Amiodarone
Benzbromarone, thebrominated analogue of benziodarone, used as anuricosuric
Dronedarone

References

Pizzichini M, Aleo MF, Marcolongo R, Marinello E (June 1982). "The mechanism of benzodiarone activity".Quaderni Sclavo di Diagnostica Clinica e di Laboratorio.18 (2):203–8.PMID 6984763.

v t e Vasodilators used incardiac diseases (C01D)
Nitrovasodilators	Nitroglycerin # Isosorbide dinitrate # Isosorbide mononitrate Itramin tosilate Linsidomine Molsidomine Nicorandil Pentaerythritol tetranitrate Propatylnitrate Tenitramine Trolnitrate
Quinolone vasodilators	Flosequinan^‡
Others	Benziodarone Carbocromen Cinepazet Cloridarol Dilazep Efloxate Etafenone Gapicomine Heptaminol Hexobendine Imolamine Levosimendan Nesiritide Nicorandil Oxyfedrine Pimobendan Prenylamine Serelaxin Trapidil Vericiguat
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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