 | |
| Clinical data | |
|---|---|
| Routes of administration | Oral |
| ATC code | |
| Identifiers | |
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| CAS Number | |
| PubChemCID | |
| ChemSpider |
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| UNII | |
| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.023.340 |
| Chemical and physical data | |
| Formula | C17H15NO5 |
| Molar mass | 313.309 g·mol−1 |
| 3D model (JSmol) | |
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 N Y (what is this?) (verify) | |
Benorilate (INN), orbenorylate, is anester-linkedcodrug ofaspirin withparacetamol. It is used as ananti-inflammatory andantipyretic medication. In the treatment of childhood fever, it has been shown to be inferior to paracetamol and aspirin taken separately. In addition, because it is converted to aspirin, benorylate is not recommended in children due to concerns aboutReye syndrome.[1]
Acetyl salicoyl chloride (1) is reacted with paracetamol (2) to give benorilate (3).[2][3][4][5]
Partialsaponification of benorilate leads toacetaminosalol (phenetsal).[6]
| pyrazolones / pyrazolidines | |
|---|---|
| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
|
| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;†withdrawn drugs;‡veterinary use. | |
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