| Bat SARS-like coronavirus WIV1 | |
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Virus classification | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | Sarbecovirus |
| Species: | |
| Strain: | Bat SARS-like coronavirus WIV1 |
| Synonyms | |
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Bat SARS-like coronavirus WIV1 (Bat SL-CoV-WIV1), also sometimes calledSARS-like coronavirus WIV1, is a strain ofsevere acute respiratory syndrome–related coronavirus (SARSr-CoV) isolated from Chinese rufous horseshoe bats in 2013 (Rhinolophus sinicus).[1][2] Like all coronaviruses, virions consist of single-strandedpositive-senseRNA enclosed within anenvelope.[3]
WIV1 was named for theWuhan Institute of Virology, where it was discovered by a researcher onShi Zhengli's team.[4]
In 2018,Ralph S. Baric and Vincent Munster ofRocky Mountain Laboratories infectedEgyptian fruit bat(Rousettus aegyptiacus) with WIV1.[5]SARS-CoV-2 transmits efficiently in Egyptian fruit bats.[6]
The discovery confirms that bats are the natural reservoir of SARS-CoV.Phylogenetic analysis shows the possibility of direct transmission ofSARS from bats to humans without the intermediary Chinesecivets, as previously believed.[7]
A phylogenetic tree based on whole-genome sequences of SARS-CoV-1 and related coronaviruses is:
| SARS‑CoV‑1 related coronavirus |
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SARS-CoV-2, 79% to SARS-CoV-1[16] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Taxonomy of theCoronaviridae | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Higher taxonomy:Riboviria >Orthornavirae >Pisuviricota >Pisoniviricetes >Nidovirales >Cornidovirineae >Coronaviridae | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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