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BRSK2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
BRSK2
Identifiers
AliasesBRSK2, C11orf7, PEN11B, SAD1, SADA, STK29, BR serine/threonine kinase 2, SAD-A
External IDsOMIM:609236;MGI:1923020;HomoloGene:123829;GeneCards:BRSK2;OMA:BRSK2 - orthologs
EC number2.7.11.26
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for BRSK2
Genomic location for BRSK2
Band11p15.5Start1,389,899bp[1]
End1,462,689bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for BRSK2
Genomic location for BRSK2
Band7|7 F5Start141,503,488bp[2]
End141,557,984bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right hemisphere of cerebellum

  • body of pancreas

  • right frontal lobe

  • ganglionic eminence

  • anterior cingulate cortex

  • Brodmann area 9

  • prefrontal cortex

  • C1 segment

  • nucleus accumbens

  • Amygdala
Top expressed in
  • visual cortex

  • primary visual cortex

  • superior frontal gyrus

  • dentate gyrus of hippocampal formation granule cell

  • neural layer of retina

  • cerebellar cortex

  • prefrontal cortex

  • hippocampus proper

  • ganglionic eminence

  • lumbar subsegment of spinal cord
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9024

75770

Ensembl

ENSG00000174672

ENSMUSG00000053046

UniProt

Q8IWQ3

Q69Z98

RefSeq (mRNA)

NM_001256627
NM_001256629
NM_001256630
NM_001282218
NM_003957

NM_001009929
NM_001009930
NM_001276763
NM_029426

RefSeq (protein)

NP_001243556
NP_001243558
NP_001243559
NP_001269147
NP_003948

NP_001009929
NP_001009930
NP_001263692
NP_083702

Location (UCSC)Chr 11: 1.39 – 1.46 MbChr 7: 141.5 – 141.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BR serine/threonine-protein kinase 2 is anenzyme that in humans is encoded by theBRSK2gene.[5][6][7]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000174672Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000053046Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Miura K, Masuzaki H, Ishimaru T, Niikawa N, Jinno Y (Jan 1999)."A HhaI/BstUI polymorphism in a novel gene at human chromosome 11p15.5".Journal of Human Genetics.43 (4):283–4.doi:10.1007/s100380050092.PMID 9852686.
  6. ^Miura K, Miyoshi O, Yun K, Inazawa J, Miyamoto T, Hayashi H, Masuzaki H, Yoshimura S, Niikawa N, Jinno Y, Ishimaru T (Mar 1999)."Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta".Journal of Human Genetics.44 (1):1–9.doi:10.1007/s100380050096.PMID 9929968.
  7. ^"Entrez Gene: BRSK2 BR serine/threonine kinase 2".

Further reading

[edit]

External links

[edit]
Non-specific serine/threonine protein kinases (EC 2.7.11.1)
Pyruvate dehydrogenase kinase (EC 2.7.11.2)
Dephospho-(reductase kinase) kinase (EC 2.7.11.3)
3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase (EC 2.7.11.4)
(isocitrate dehydrogenase (NADP+)) kinase (EC 2.7.11.5)
(tyrosine 3-monooxygenase) kinase (EC 2.7.11.6)
Myosin-heavy-chain kinase (EC 2.7.11.7)
Fas-activated serine/threonine kinase (EC 2.7.11.8)
Goodpasture-antigen-binding protein kinase (EC 2.7.11.9)
  • -
IκB kinase (EC 2.7.11.10)
cAMP-dependent protein kinase (EC 2.7.11.11)
cGMP-dependent protein kinase (EC 2.7.11.12)
Protein kinase C (EC 2.7.11.13)
Rhodopsin kinase (EC 2.7.11.14)
Beta adrenergic receptor kinase (EC 2.7.11.15)
G-protein coupled receptor kinases (EC 2.7.11.16)
Ca2+/calmodulin-dependent (EC 2.7.11.17)
Myosin light-chain kinase (EC 2.7.11.18)
Phosphorylase kinase (EC 2.7.11.19)
Elongation factor 2 kinase (EC 2.7.11.20)
Polo kinase (EC 2.7.11.21)
Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30)
Polo kinase (EC 2.7.11.21)
Cyclin-dependent kinase (EC 2.7.11.22)
(RNA-polymerase)-subunit kinase (EC 2.7.11.23)
Mitogen-activated protein kinase (EC 2.7.11.24)
MAP3K (EC 2.7.11.25)
Tau-protein kinase (EC 2.7.11.26)
(acetyl-CoA carboxylase) kinase (EC 2.7.11.27)
  • -
Tropomyosin kinase (EC 2.7.11.28)
  • -
Low-density-lipoprotein receptor kinase (EC 2.7.11.29)
  • -
Receptor protein serine/threonine kinase (EC 2.7.11.30)
MAP2K
Activity
Regulation
Classification
Kinetics
Types
Portal:
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