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BNIPL

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
BNIPL
Identifiers
AliasesBNIPL, BNIP-S, BNIPL-1, BNIPL-2, BNIPL1, BNIPL2, BNIPS, PP753, BCL2/adenovirus E1B 19kD interacting protein like, BNIP-Salpha, BNIP-Sbeta, BCL2 interacting protein like
External IDsOMIM:611275;MGI:2384749;HomoloGene:15900;GeneCards:BNIPL;OMA:BNIPL - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for BNIPL
Genomic location for BNIPL
Band1q21.3Start151,036,321bp[1]
End151,047,720bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for BNIPL
Genomic location for BNIPL
Band3|3 F2.1Start95,148,582bp[2]
End95,158,504bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of arm

  • skin of abdomen

  • amniotic fluid

  • skin of leg

  • skin of thigh

  • skin of hip

  • gingival epithelium

  • oral cavity

  • mucosa of pharynx

  • buccal mucosa cell
Top expressed in
  • lip

  • esophagus

  • zone of skin

  • urinary bladder

  • urethra

  • female urethra

  • morula

  • male urethra

  • epithelium of urethra

  • epithelium of male urethra
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

149428

171388

Ensembl

ENSG00000163141

ENSMUSG00000028115

UniProt

Q7Z465

Q99JU7

RefSeq (mRNA)

NM_001159642
NM_138278
NM_138279

NM_001168356
NM_134253

RefSeq (protein)

NP_001153114
NP_612122

NP_001161828
NP_599014

Location (UCSC)Chr 1: 151.04 – 151.05 MbChr 3: 95.15 – 95.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein is aprotein that in humans is encoded by theBNIPLgene.[5][6][7]

Interactions

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BNIPL has been shown tointeract with:

References

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  1. ^abcGRCh38: Ensembl release 89: ENSG00000163141Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000028115Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^abcShen L, Hu J, Lu H, Wu M, Qin W, Wan D, Li YY, Gu J (Apr 2003)."The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER".FEBS Letters.540 (1–3):86–90.doi:10.1016/S0014-5793(03)00229-1.PMID 12681488.
  6. ^Zhou YT, Soh UJ, Shang X, Guy GR, Low BC (Mar 2002)."The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequence".The Journal of Biological Chemistry.277 (9):7483–92.doi:10.1074/jbc.M109459200.PMID 11741952.
  7. ^"Entrez Gene: BNIPL BCL2/adenovirus E1B 19kD interacting protein like".
  8. ^abcQin W, Hu J, Guo M, Xu J, Li J, Yao G, Zhou X, Jiang H, Zhang P, Shen L, Wan D, Gu J (Aug 2003). "BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis".Biochemical and Biophysical Research Communications.308 (2):379–85.doi:10.1016/s0006-291x(03)01387-1.PMID 12901880.
  9. ^abYasuda M, Han JW, Dionne CA, Boyd JM, Chinnadurai G (Feb 1999). "BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3".Cancer Research.59 (3):533–7.PMID 9973195.

External links

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Further reading

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