 | This articleneeds additional citations forverification. Please helpimprove this article byadding citations to reliable sources. Unsourced material may be challenged and removed. Find sources: "Azlocillin" – news ·newspapers ·books ·scholar ·JSTOR(August 2013) (Learn how and when to remove this message) |
 | |
| Clinical data | |
|---|---|
| Trade names | Securopen |
| AHFS/Drugs.com | International Drug Names |
| ATC code | |
| Identifiers | |
| |
| CAS Number | |
| PubChemCID | |
| DrugBank |
|
| ChemSpider |
|
| UNII | |
| KEGG |
|
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.048.483 |
| Chemical and physical data | |
| Formula | C20H23N5O6S |
| Molar mass | 461.49 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
| (verify) | |
Azlocillin is anacylampicillinantibiotic with an extended spectrum of activity and greaterin vitro potency than the carboxypenicillins.Azlocillin is similar tomezlocillin andpiperacillin. It demonstrates antibacterial activity against a broad spectrum ofbacteria, includingPseudomonas aeruginosa, and, in contrast to mostcephalosporins, exhibits activity againstenterococci.
Azlocillin is considered a broad spectrum antibiotic and can be used against a number of Gram positive and Gram negative bacteria. The following represents MIC susceptibility data for a few medically significant organisms.[1]
An interesting alternative synthesis of azlocillin involves activation of the substitutedphenylglycine analogue1 with 1,3-dimethyl-2-chloro-1-imidazolinium chloride (2) and then condensation with6-APA.
