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Arnolol

From Wikipedia, the free encyclopedia

Chemical compound

Pharmaceutical compound

Arnolol
Clinical data

ATC code	none
Identifiers
IUPAC name 3-amino-1-[4-(2-methoxyethyl)phenoxy]-3-methyl-butan-2-ol
CAS Number	87129-71-3^N
PubChemCID	65653
ChemSpider	59090^Y
UNII	98HS077RUP
ChEMBL	ChEMBL1742421^N
CompTox Dashboard(EPA)	DTXSID80868963
Chemical and physical data
Formula	C₁₄H₂₃NO₃
Molar mass	253.342 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O(c1ccc(cc1)CCOC)CC(O)C(N)(C)C
InChI InChI=1S/C14H23NO3/c1-14(2,15)13(16)10-18-12-6-4-11(5-7-12)8-9-17-3/h4-7,13,16H,8-10,15H2,1-3H3^Y Key:LAWLHMWODZUZJH-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Arnolol is abeta blocker.^[1]^[2]

References

^"The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs". Archived fromthe original on March 7, 2012.
^Safi S, Korang SK, Nielsen EE, Sethi NJ, Feinberg J, Gluud C, Jakobsen JC (2021)."Beta‐blockers for heart failure".Cochrane Database of Systematic Reviews.7.doi:10.1002/14651858.CD012897.pub2.PMC 8253168.

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Sympatholytic (and closely related)antihypertensives (C02)

Sympatholytics
(antagonizeα-adrenergic
vasoconstriction)

Central

α₂-Adrenergic receptor agonists	Clonidine Guanabenz Guanfacine Guanoxabenz Methyldopa^# Tiamenidine^‡
Adrenergic release inhibitors	Bethanidine Bretylium Debrisoquine Guanadrel Guanazodine Guancydine Guanethidine Guanoclor Guanoxan
Imidazoline receptor agonists	Moxonidine Rilmenidine Tolonidine
Ganglion-blocking/nicotinic antagonists	Hexamethonium^‡ Mecamylamine Pentolinium Trimethaphan

Peripheral

Indirect

Monoamine oxidase inhibitors	Pargyline^‡
VMAT inhibitors	Bietaserpine Deserpidine Methoserpidine Reserpine Syrosingopine
Tyrosine hydroxylase inhibitors	Metirosine

Direct

α₁-Adrenergic receptor blockers	Doxazosin Ketanserin Indoramin Prazosin Trimazosin Urapidil
Non-selective α-adrenergic receptor blockers	Phentolamine

Otherantagonists

Serotonin receptor antagonists	Ketanserin Lidanserin
Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension)	dual (Aprocitentan,Bosentan,Macitentan (+tadalafil),Riociguat) selective (Ambrisentan (+tadalafil),Sitaxentan,Sotatercept)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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Adrenergic receptor modulators

Agonists

Antagonists

Agonists

Antagonists

Agonists

Antagonists

See also:Receptor/signaling modulators
Dopaminergics
Serotonergics
Monoamine reuptake inhibitors
Monoamine releasing agents
Monoamine metabolism modulators
Monoamine neurotoxins

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