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Arformoterol

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Arformoterol
Clinical data
Trade namesBrovana
Other namesArformoterol tartrate (USANUS)
AHFS/Drugs.comMonograph
MedlinePlusa602023
License data
Routes of
administration
Inhalation
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Protein binding52–65%
Eliminationhalf-life26 hours
Identifiers
  • N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl) propan-2-yl]amino]ethyl] phenyl]formamide
CAS Number
PubChemCID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC19H24N2O4
Molar mass344.411 g·mol−1
  • InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1 checkY
  • Key:BPZSYCZIITTYBL-YJYMSZOUSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Arformoterol, sold under the brand nameBrovana among others, is amedication used for the treatment ofchronic obstructive pulmonary disease (COPD).[1][2]

It is along-acting β2 adrenoreceptor agonist (LABA) and it is the active (R,R)-(−)-enantiomer offormoterol.[1] It was approved for medical use in the United States in October 2006.[1] It is available as ageneric medication.[3]

Medical uses

[edit]

Arformoterol isindicated for the maintenance treatment of bronchoconstriction in people with chronic obstructive pulmonary disease (COPD).[1]

References

[edit]
  1. ^abcde"Brovana- arformoterol tartrate solution".DailyMed. 13 May 2021. Retrieved4 March 2022.
  2. ^Loh CH, Donohue JF, Ohar JA (March 2015). "Review of drug safety and efficacy of arformoterol in chronic obstructive pulmonary disease".Expert Opinion on Drug Safety.14 (3):463–72.doi:10.1517/14740338.2015.998196.PMID 25563342.S2CID 7767810.
  3. ^"Competitive Generic Therapy Approvals".U.S.Food and Drug Administration (FDA). 29 June 2023. Archived fromthe original on 29 June 2023. Retrieved29 June 2023.

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