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Arbutamine

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Chemical compound

Pharmaceutical compound

Arbutamine
Clinical data

ATC code	C01CA22 (WHO)
Identifiers
IUPAC name 4-[(1R)-1-hydroxy-2-{[4-(4-hydroxyphenyl)butyl]amino}ethyl]benzene-1,2-diol
CAS Number	128470-16-6^Y
PubChemCID	60789
DrugBank	DB01102^Y
ChemSpider	54785^Y
UNII	B07L15YAEV
ChEBI	CHEBI:50580^Y
ChEMBL	ChEMBL1201251^N
CompTox Dashboard(EPA)	DTXSID00155908
Chemical and physical data
Formula	C₁₈H₂₃NO₄
Molar mass	317.385 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Oc1ccc(cc1O)[C@@H](O)CNCCCCc2ccc(O)cc2
InChI InChI=1S/C18H23NO4/c20-15-7-4-13(5-8-15)3-1-2-10-19-12-18(23)14-6-9-16(21)17(22)11-14/h4-9,11,18-23H,1-3,10,12H2/t18-/m0/s1^Y Key:IIRWWTKISYTTBL-SFHVURJKSA-N^Y
^NY (what is this?) (verify)

Arbutamine is acardiac stimulant. It stimulates βadrenergic receptors.^[1]

^Abou-Mohamed G, Nagarajan R, Ibrahim TM, Caldwell RW (March 1996). "Characterization of the adrenergic activity of arbutamine, a novel agent for pharmacological stress testing".Cardiovascular Drugs and Therapy.10 (1):39–47.doi:10.1007/BF00051129.PMID 8723169.S2CID 30315981.

Agonists

Antagonists

Agonists

Antagonists

Agonists

Antagonists

Cardiac stimulants excluding cardiac glycosides (C01C)

α	Denopamine Metaraminol Methoxamine Midodrine Norfenefrine Oxedrine Phenylephrine
β	Arbutamine Dobutamine Isoprenaline Prenalterol
mixed	Amezinium metilsulfate Droxidopa Epinephrine # Etilefrine Norepinephrine

Both

Unknown/ungrouped

Other cardiac stimulants

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