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Angiokeratoma

From Wikipedia, the free encyclopedia
Medical condition
Angiokeratoma
SpecialtyOncology,dermatology Edit this on Wikidata

Angiokeratoma is a benigncutaneous lesion of capillaries, resulting in small marks of red to blue color and characterized byhyperkeratosis.Angiokeratoma corporis diffusum refers toFabry's disease,[1] but this is usually considered a distinct condition.

Signs and symptoms

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Presentation includestelangiectasia,acanthosis, andhyperkeratosis.[2]

Presentation can be solitary or systemic.[3]

Multiple angiokeratomas, especially on the trunk in young people, are typical forFabry disease, genetic disorder connected with systemic complications.

Complications

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In some instances nodular angiokeratomas can produce necrotic tissue and valleys that can harbor fungal, bacterial and viral infections. Infections can include staphylococcus. If the lesion becomes painful, begins draining fluids or pus, or begins to smell, a doctor may recommend excision and grafting.

Pathophysiology

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Histology

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Angiokeratomas characteristically have large dilatedblood vessels in the superficialdermis andhyperkeratosis (overlying the dilated vessels).

  • Scrotal angiokeratoma; visible large dilated blood vessels and hyperkeratosis
    Scrotal angiokeratoma; visible large dilated blood vessels andhyperkeratosis
  • Scrotal angiokeratoma (Fordyce type); multiple papules made by dilatated capillaries
    Scrotal angiokeratoma (Fordyce type); multiplepapules made by dilatatedcapillaries
  • Scrotal angiokeratoma (Fordyce type); dilated cavernous capillaries, acanthosis
    Scrotal angiokeratoma (Fordyce type); dilated cavernous capillaries,acanthosis
  • Scrotal angiokeratoma (Mibelli type); blood vessels close to the epidermis
    Scrotal angiokeratoma (Mibelli type); blood vessels close to theepidermis
  • Angiokeratoma (Mibelli type)
    Angiokeratoma (Mibelli type)

Diagnosis

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Classification

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Angiokeratoma may be classified as:

  • Angiokeratoma of Mibelli (also known as "Mibelli's angiokeratoma,"[4] "Telangiectatic warts"[5]) consists of 1- to 5-mm red vascular papules, the surfaces of which become hyperkeratotic in the course of time.[5]: 589  The disease is named after ItaliandermatologistVittorio Mibelli (1860-1910).[6]
  • Angiokeratoma ofFordyce (also known as "Angiokeratoma of the scrotum and vulva," though not to be confused withFordyce's spots)[5] is a skin condition characterized by red to blue papules on the scrotum or vulva.
  • Solitary angiokeratoma is a small, bluish-black, wartypapule that occurs predominantly on the lower extremities.[5]: 590 
  • Verrucous vascular malformation (also known as "Angiokeratoma circumscriptum naeviforme") is a malformation ofdermal and subcutaneouscapillaries andveins, a congenitalvascular malformation, which, over time, a verrucous component appears.[5]: 584 

Treatment

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Different treatment options exist including cryotherapy, laser therapy, and excision.

See also

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References

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  1. ^Trickett R, Dowd H (October 2006)."Angiokeratoma of the scrotum: a case of scrotal bleeding".Emerg Med J.23 (10): e57.doi:10.1136/emj.2006.038745.PMC 2579622.PMID 16988295.
  2. ^"angiokeratoma" atDorland's Medical Dictionary
  3. ^Sion-Vardy N, Manor E, Puterman M, Bodner L (January 2008)."Solitary angiokeratoma of the tongue"(PDF).Med Oral Patol Oral Cir Bucal.13 (1): E12–4.PMID 18167473.
  4. ^Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).Dermatology: 2-Volume Set. St. Louis: Mosby.ISBN 978-1-4160-2999-1.
  5. ^abcdeJames, William; Berger, Timothy; Elston, Dirk (2005).Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders.ISBN 0-7216-2921-0.
  6. ^Mibelli's disease II @Who Named It

External links

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Classification
External resources
Blood vessel
Lymphatic
Either
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