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Anaprazole

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Pharmaceutical compound

Anaprazole
Identifiers

IUPAC name 2-[[3-(3-methoxypropoxy)-2-methylphenyl]methylsulfinyl]-6,7-dihydro-1H-furo[2,3-f]benzimidazole
PubChemCID	156009457
ChemSpider	128732661 Na⁺ salt: 128433794
UNII	W6OO9ZB0FC
ChEMBL	ChEMBL4651083 Na⁺ salt: ChEMBL4650347
Chemical and physical data
Formula	C₂₁H₂₄N₂O₄S
Molar mass	400.49 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1=C(C=CC=C1OCCCOC)CS(=O)C2=NC3=C(N2)C=C4CCOC4=C3
InChI InChI=InChI=1S/C21H24N2O4S/c1-14-16(5-3-6-19(14)26-9-4-8-25-2)13-28(24)21-22-17-11-15-7-10-27-20(15)12-18(17)23-21/h3,5-6,11-12H,4,7-10,13H2,1-2H3,(H,22,23) Key:JYSIFLQJDVIWKM-UHFFFAOYSA-N

Anaprazole is a pharmaceutical drug used for the treatment ofduodenal ulcers. It is classified as aproton pump inhibitor (PPI).^[1] It was approved for use in China in 2023.^[2] It is formulated as its sodium salt, anaprazole sodium, inenteric-coated tablets.^[2]

^Wang F, Niu X, Liu F, Ma X, Cheng F, Xu H, et al. (July 2024). "Safety, Tolerability, and Pharmacokinetics of Anaprazole, a Novel Proton Pump Inhibitor, in Healthy Chinese Subjects".Clinical Pharmacology in Drug Development.13 (7):782–789.doi:10.1002/cpdd.1405.PMID 38629191.
^^a ^b"Anaprazole Sodium Enteric-coated Tablets Approved for Marketing by China NMPA". ChineseNational Medical Products Administration. 2023-06-25.

v t e Drugs forpeptic ulcer andGERD/GORD (A02B)
H₂ antagonists ("-tidine")	Cimetidine Famotidine Lafutidine Lavoltidine (loxtidine) Niperotidine Nizatidine Ranitidine^# Roxatidine
Prostaglandins (E)/ analogues ("-prost-")	Misoprostol Enprostil
Proton-pump inhibitors ("-prazole")	Anaprazole Azeloprazole Dexlansoprazole Dexrabeprazole Esomeprazole Ilaprazole Lansoprazole Omeprazole^# Pantoprazole Picoprazole Rabeprazole Tenatoprazole Timoprazole
Potassium-competitive acid blockers ("-prazan")	Fexuprazan Linaprazan Revaprazan Soraprazan Tegoprazan Vonoprazan Zastaprazan
Others	Aceglutamide aluminum Acetoxolone Alginic acid Arbaclofen placarbil Bismuth subcitrate Carbenoxolone Cetraxate Gefarnate Irsogladine Lesogaberan Pirenzepine Proglumide Rebamipide Sucralfate Sulglicotide Telenzepine Teprenone Troxipide Zinc L-carnosine Zolimidine
Combinations	Bismuth subcitrate/metronidazole/tetracycline Omeprazole/amoxicillin/rifabutin Vonoprazan/amoxicillin Vonoprazan/amoxicillin/clarithromycin
See also:Helicobacter pylori* eradication protocols*
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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