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Amfenac

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Amfenac
Clinical data
ATC code
  • none
Identifiers
  • (2-Amino-3-benzoylphenyl)acetic acid
CAS Number
PubChemCID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC15H13NO3
Molar mass255.273 g·mol−1
3D model (JSmol)
  • O=C(c1cccc(c1N)CC(=O)O)c2ccccc2
  • InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18) checkY
  • Key:SOYCMDCMZDHQFP-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Amfenac, also known as2-amino-3-benzoylbenzeneacetic acid, is anonsteroidal anti-inflammatory drug (NSAID) withacetic acidmoiety.[1]

See also

[edit]
  • Bromfenac (same structure as amfenac but withp-bromo)

References

[edit]
  1. ^Hiranuma T, Kato S, Hachisu M (September 1988)."Analgesic action of amfenac Na, a non-steroidal anti-inflammatory agent".Journal of Pharmacobio-Dynamics.11 (9):612–9.doi:10.1248/bpb1978.11.612.PMID 3265150.
pyrazolones /
pyrazolidines
salicylates
acetic acid derivatives
and related substances
oxicams
propionic acid
derivatives (profens)
n-arylanthranilic
acids (fenamates)
COX-2 inhibitors
(coxibs)
other
NSAID
combinations
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;withdrawn drugs;veterinary use.
Receptor
(ligands)
DP (D2)Tooltip Prostaglandin D2 receptor
DP1Tooltip Prostaglandin D2 receptor 1
DP2Tooltip Prostaglandin D2 receptor 2
EP (E2)Tooltip Prostaglandin E2 receptor
EP1Tooltip Prostaglandin EP1 receptor
EP2Tooltip Prostaglandin EP2 receptor
EP3Tooltip Prostaglandin EP3 receptor
EP4Tooltip Prostaglandin EP4 receptor
Unsorted
FP (F)Tooltip Prostaglandin F receptor
IP (I2)Tooltip Prostacyclin receptor
TP (TXA2)Tooltip Thromboxane receptor
Unsorted
Enzyme
(inhibitors)
COX
(
PTGS)
PGD2STooltip Prostaglandin D synthase
PGESTooltip Prostaglandin E synthase
PGFSTooltip Prostaglandin F synthase
PGI2STooltip Prostacyclin synthase
TXASTooltip Thromboxane A synthase
Others


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