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Alizapride

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Chemical compound
Pharmaceutical compound
Alizapride
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral,IM,IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Eliminationhalf-life3 hours
ExcretionRenal
Identifiers
  • N-[(1-Allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.056.082Edit this at Wikidata
Chemical and physical data
FormulaC16H21N5O2
Molar mass315.377 g·mol−1
3D model (JSmol)
  • C=CCN1CCCC1CNC(=O)c3cc2nn[nH]c2cc3OC
  • InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20) checkY
  • Key:KSEYRUGYKHXGFW-UHFFFAOYSA-N checkY
  (verify)

Alizapride (Litican,Plitican,Superan,Vergentan) is adopamine antagonist withprokinetic andantiemetic effects used in the treatment ofnausea andvomiting, includingpostoperative nausea and vomiting. It is structurally related tometoclopramide and otherbenzamides.[1]

References

[edit]
  1. ^Ballatori E, Roila F (September 2003)."Impact of nausea and vomiting on quality of life in cancer patients during chemotherapy".Health and Quality of Life Outcomes.1: 46.doi:10.1186/1477-7525-1-46.PMC 212194.PMID 14521717.
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