Anadenovirus vaccine is avaccine againstadenovirus infection.[3] According to the AmericanCDC, "There is currently no adenovirus vaccine available to the general public.[4]
It was used by theUnited States military from 1971 to 1999, but was discontinued when the only manufacturer stopped production.[8][9] This vaccine elicited immunity to adenovirusserotypes 4 and 7,[10] the serotypes most often associated with acute respiratory disease. On 16 March 2011, theU.S. Food and Drug Administration approved an adenovirus vaccine manufactured byTeva Pharmaceuticals under contract to the U.S. Army.[11] This vaccine is essentially the same as the one used from 1971 to 1999. On 24 October 2011, the military services began administering the new adenovirus vaccine to recruits during basic training.[12]
The vaccine is orally administered and consists of live (notattenuated) virus. The tablets are coated, so that the virus passes the stomach and infects the intestines, where the immune response is raised.[13]
^Centers for Disease Control and Prevention (CDC) (July 2001). "Two fatal cases of adenovirus-related illness in previously healthy young adults--Illinois, 2000".MMWR Morb. Mortal. Wkly. Rep.50 (26):553–5.PMID11456329.
^Malarkey MA, Baylor NW. FDA approval letter dated 16 March 2011.
