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AdCLD-CoV19

From Wikipedia, the free encyclopedia
Vaccine candidate against COVID-19

Pharmaceutical compound
AdCLD-CoV19
Vaccine description
TargetSARS-CoV-2
Vaccine typeViral vector
Clinical data
Routes of
administration
Intramuscular
Identifiers
CAS Number
Part ofa series on the
COVID-19 pandemic
Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
virus iconCOVID-19 portal

AdCLD-CoV19 is aCOVID-19 vaccine candidate developed by Cellid Co,[2][3] a company from South Korea.[4]

A phase 1/2 trial of a single injection of AdCLD-CoV19 began in December 2020 in South Korea.[5] In September 2021, a phase 1 trial began for a single injection of another version, named AdCLD-CoV19-1.[6]Preclinical studies of a single dose in mice and non-human primates for this vaccine candidate were published in April 2022.[7] In August 2022, a phase 2 trial of 1 or 2 doses of AdCLD-CoV19-1 was registered.[8]

References

[edit]
  1. ^"Patent Landscape Report COVID-19-related vaccines and therapeutics"(PDF).
  2. ^Chan-Hyuk K (10 December 2020)."LG Chem pushes for Covid-19 vaccine CMO deal".Korea Biomedical Review. Retrieved22 August 2021.
  3. ^Chan-hyuk K (11 August 2021)."Covid-19 vaccine trials stalled by rare chance to get licensed vaccines".Korea Biomedical Review. Retrieved22 August 2021.
  4. ^"Cellid Co Ltd, Company Profile and News".Bloomberg Markets.
  5. ^Clinical trial numberNCT04666012 for "Safety and Immunogenicity Study of AdCLD-CoV19: A COVID-19 Preventive Vaccine in Healthy Volunteers" atClinicalTrials.gov
  6. ^Cellid Co (21 January 2022)."A Dose Escalation, Multicenter, Open, Phase I Study to Assess the Safety and Immunogenicity of AdCLD-CoV19-1, a COVID-19 Preventive Vaccine in Healthy Volunteers".clinicaltrials.gov. National Institutes of Health. Retrieved27 September 2022.
  7. ^Shin SP, Shin KS, Lee JM, Jung IK, Koo J, Lee SW, et al. (April 2022)."The Chimeric Adenovirus (Ad5/35) Expressing Engineered Spike Protein Confers Immunity against SARS-CoV-2 in Mice and Non-Human Primates".Vaccines.10 (5): 712.doi:10.3390/vaccines10050712.PMC 9147121.PMID 35632468.
  8. ^Cellid Co (27 August 2022)."A Phase IIb, Multicenter, Observer-Blinded, Randomized, Placebo-Controlled Trial to Evaluate the Immunogenicity and Safety of the AdCLD-CoV19-1 in Healthy Adults Aged 19 Years Old and Above".clinicaltrials.gov. National Institutes of Health. Retrieved27 September 2022.
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