 | |
| Identifiers | |
|---|---|
| |
| CAS Number | |
| PubChemCID | |
| ChemSpider |
|
| UNII | |
| ChEMBL | |
| Chemical and physical data | |
| Formula | C26H34O2 |
| Molar mass | 378.556 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
| (verify) | |
AM-411 (part of theAM cannabinoid series) is ananalgesic drug that is acannabinoidagonist. It is a derivative of Δ8-THC substituted with anadamantyl group at the 3-position, demonstrating that the binding pocket for thealkyl chain at this position can accommodate significant bulk.
AM-411 is a potent and fairly selective CB1 full agonist with aKi of 6.80 nM, but is still also a moderately potent CB2 agonist with a Ki of 52.0 nM.[1] It produces similar effects to other cannabinoid agonists such asanalgesia,sedation, andanxiolysis.[2][3]
 | Thiscannabinoid related article is astub. You can help Wikipedia byexpanding it. |
