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Adamantyl-THPINACA

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(Redirected fromADAMANTYL-THPINACA)
Chemical compound
Pharmaceutical compound
Adamantyl-THPINACA
Legal status
Legal status
Identifiers
  • N-(2-Adamantyl)-1-(tetrahydropyran-4-ylmethyl)indazole-3-carboxamide
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC24H31N3O2
Molar mass393.531 g·mol−1
3D model (JSmol)
  • C12C(C3CC(CC(C1)C3)C2)NC(=O)C2=NN(C3=CC=CC=C23)CC2CCOCC2
  • InChI=1/C24H31N3O2/c28-24(25-22-18-10-16-9-17(12-18)13-19(22)11-16)23-20-3-1-2-4-21(20)27(26-23)14-15-5-7-29-8-6-15/h1-4,15-19,22H,5-14H2,(H,25,28)/f/h25H
  • Key:XFZLBNDGZVRJNJ-UHFFFAOYSA-N

Adamantyl-THPINACA (ATHPINACA,AD-THPINACA)[1] is anindazole-basedsynthetic cannabinoid,[2] which was first reported toEuropol in Slovenia in January 2015.[3] It is known as both the 1-adamantyl and 2-adamantyl isomers (SGT-40 andSGT-194 respectively), which can be distinguished byGC-EI-MS.[4] It is banned in Sweden[5] andRussia.[6] Both the 1-adamantyl and 2-adamantyl isomers are specifically listed as illegal drugs in Japan.[7] Given the known metabolic liberation (and presence as an impurity) ofamantadine in the related compoundAPINACA, it is suspected that metabolichydrolysis of the amide group of Adamantyl-THPINACA may also release amantadine.

See also

[edit]

References

[edit]
  1. ^"ATHPINACA isomer 1 (CAS 1400742-48-4)". Caymen Chemical. Retrieved29 April 2017.
  2. ^"Muuntohuumeiden esiintyvyys 2015"(PDF). Finnish Medicines Agency. 7 May 2015. Retrieved10 March 2021.
  3. ^Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA
  4. ^Asada A, Doi T, Tagami T, Takeda A, Sawabe Y (March 2017). "Isomeric discrimination of synthetic cannabinoids by GC-EI-MS: 1-adamantyl and 2-adamantyl isomers of N-adamantyl carboxamides".Drug Testing and Analysis.9 (3):378–388.doi:10.1002/dta.2124.PMID 27770510.
  5. ^"Fler ämnen föreslås bli klassade som narkotika eller hälsofarlig vara". Folkhälsomyndigheten. Retrieved24 July 2015.
  6. ^List of substances prohibited in the Russian Federation
  7. ^指定薬物一覧
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