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60S ribosomal protein L9

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From Wikipedia, the free encyclopedia

Protein found in humans

RPL9

Available structures

PDB

Ortholog search:PDBe RCSB

List of PDB id codes
2CQL,4UG0,4V6X,5AJ0,3J92,4UJC,3J7P,4UJE,3J7Q,3J7R,4D67,4UJD,4V5Z,4D5Y,3J7O

Identifiers

Aliases

RPL9, L9, NPC-A-16, ribosomal protein L9

External IDs

OMIM:603686;MGI:1298373;HomoloGene:90855;GeneCards:RPL9;OMA:RPL9 - orthologs

Gene location (Human)

Chr.	Chromosome 4 (human)^[1]

Band	4p14	Start	39,452,587bp^[1]
Band	4p14	End	39,458,931bp^[1]

Gene location (Mouse)

Chr.	Chromosome 5 (mouse)^[2]

Band	5\|5 C3.1	Start	65,545,707bp^[2]
Band	5\|5 C3.1	End	65,548,787bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

left ovary

right ovary

gastric mucosa

Achilles tendon

right uterine tube

ganglionic eminence

lactiferous gland

corpus callosum

olfactory zone of nasal mucosa

gallbladder

Top expressed in

dentate gyrus of hippocampal formation granule cell

ventricular zone

blastocyst

embryo

embryo

morula

superior frontal gyrus

primary visual cortex

spermatocyte

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	rRNA binding protein binding RNA binding structural constituent of ribosome
Cellular component	cytosol ribosome membrane focal adhesion intracellular anatomical structure cytosolic large ribosomal subunit nucleus extracellular matrix
Biological process	cytoplasmic translation protein biosynthesis viral transcription SRP-dependent cotranslational protein targeting to membrane translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing
Sources:Amigo /QuickGO

Orthologs

Species

Human

Mouse

Entrez


6133


20005

Ensembl


ENSG00000163682


ENSMUSG00000047215

UniProt


P32969


P51410

RefSeq (mRNA)


NM_000661 NM_001024921


NM_011292

RefSeq (protein)


NP_000652 NP_001020092


NP_035422

Location (UCSC)

Chr 4: 39.45 – 39.46 Mb

Chr 5: 65.55 – 65.55 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

60S ribosomal protein L9 is aprotein that in humans is encoded by theRPL9gene.^[5]^[6]^[7]

Ribosomes, theorganelles that catalyzeprotein synthesis, consist of a small40S subunit and a large60S subunit. Together these subunits are composed of 4RNA species and approximately 80 structurally distinct proteins. This gene encodes aribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of ribosomal proteins. It is located in thecytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processedpseudogenes of this gene dispersed through the genome. Twoalternatively spliced transcript variants encoding the same protein have been found for this gene.^[7]

References

[edit]

^^a ^b ^cGRCh38: Ensembl release 89: ENSG00000163682 –Ensembl, May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000047215 –Ensembl, May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Mazuruk K, Schoen TJ, Chader GJ, Iwata T, Rodriguez IR (Apr 1996). "Structural organization and chromosomal localization of the human ribosomal protein L9 gene".Biochim Biophys Acta.1305 (3):151–62.doi:10.1016/0167-4781(95)00201-4.PMID 8597601.
^Hori N, Murakawa K, Matoba R, Fukushima A, Okubo K, Matsubara K (Nov 1993)."A new human ribosomal protein sequence, homologue of rat L9".Nucleic Acids Res.21 (18): 4395.doi:10.1093/nar/21.18.4395.PMC 310081.PMID 8415001.
^^a ^b"Entrez Gene: RPL9 ribosomal protein L9".

External links

[edit]

PDBe-KB provides an overview of all the structure information available in the PDB for Human 60S ribosomal protein L9

v t e PDB gallery
2cql: Solution structure of the N-terminal domain of human ribosomal protein L9

Protein biosynthesis:translation (bacterial,archaeal,eukaryotic)

Proteins

eIF1	eIF1 B SUI1 family eIF1A Y
eIF2	α kinase β γ eIF2A eIF2B 1 2 3 4 5 eIF2D
eIF3	A B C D E F G H I J K L M
eIF4	A 1 2 3 E1 2 3 G 1 2 3 B H
eIF5	EIF5 EIF5A 2 5B
eIF6	EIF6

Elongation factor

Bacterial/Mitochondrial	EF-Tu EF-Ts EF-G EF-4 EF-P TSFM GFM1 GFM2
Archaeal/Eukaryotic	a/eEF-1 A1 2 3 B P1 P2 P3 D E G a/eEF-2

Release factor

Class 1
- eRF1
Class 2/RF3
- GSPT1
- GSPT2

Ribosomal Proteins

Cytoplasmic

60S subunit	RPL3 RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL10A RPL10-like RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23 RPL23A RPL24 RPL26 RPL27 RPL27A RPL28 RPL29 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL37 RPL37A RPL38 RPL39 RPL40 RPL41 RPLP0 RPLP1 RPLP2 RRP15-like RSL24D1
40S subunit	RPSA RPS2 RPS3 RPS3A RPS4 (RPS4X,RPS4Y1,RPS4Y2) RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPS30 RACK1

Mitochondrial

39S subunit	MRPL1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42
28S subunit	MRPS1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35

Other concepts

Ribosomal RNA /ribosome subunits

Archaea
(70S)

Large (50S):

Small (30S):

Bacteria
(70S)

Large (50S):

Small (30S):

Eukaryotes

Cytoplasmic (80S)	Large (60S): 5S 5.8S 28S Small (40S): 18S
Mitochondrial (55S)	Large (28S): MT-RNR2, 16S MT-tRNA^Val Small (39S): MT-RNR1, 12S
Chloroplast (70S)	Large (50S): 5S 4.5S 23S Small (30S): 16S

Ribosomal proteins

(See article table)

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