5F-NNE1

Legal status
Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Class B
Identifiers
IUPAC name 1-(5-Fluoropentyl)-N-(naphthalen-1-yl)-1H-indole-3-carboxamide
CAS Number	1445580-60-8
PubChemCID	118796566
ChemSpider	29341632
UNII	3T22QDP4D9
CompTox Dashboard(EPA)	DTXSID901032710
Chemical and physical data
Formula	C24H23FN2O
Molar mass	374.459 g·mol−1
3D model (JSmol)	Interactive image
SMILES FCCCCCn1cc(c2c1cccc2)C(=O)Nc1cccc2c1cccc2
InChI InChI=1S/C24H23FN2O/c25-15-6-1-7-16-27-17-21(20-12-4-5-14-23(20)27)24(28)26-22-13-8-10-18-9-2-3-11-19(18)22/h2-5,8-14,17H,1,6-7,15-16H2,(H,26,28) Key:DJKVOBZLMBHFKX-UHFFFAOYSA-N

5F-NNE1 (also known as5F-NNEI and5F-MN-24) is anindole-basedsynthetic cannabinoid that is presumed to be a potentagonist of theCB₁ receptor and has been sold online as adesigner drug.^[1][2] Given the known metabolic liberation (and presence as an impurity) ofamantadine in the related compoundAPINACA, it is suspected that metabolic hydrolysis of the amide group of 5F-NNE1 may release1-naphthylamine, a knowncarcinogen.

Sweden's public health agency suggested classifying 5F-NNE1 as hazardous substance on November 10, 2014.^[3]

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